| 2027 | Spaceballs: The New One | President Skroob / Yogurt | Film |
| 2027 | Spaceballs: The New One | Producer | Film |
| 2026 | The Land of Sometimes | The Postman (voice) | Film |
| 2026 | Mel Brooks: The 99 Year Old Man! | Self | TV |
| 2025 | John Candy: I Like Me | Self - Director, Spaceballs | Film |
| 2024 | Remembering Gene Wilder | Self | Film |
| 2023 | History of the World: Part II | Narrator (voice) | TV |
| 2023 | History of the World: Part II | Executive Producer | TV |
| 2022 | Paws of Fury: The Legend of Hank | Shogun (voice) | Film |
| 2022 | Paws of Fury: The Legend of Hank | Executive Producer | Film |
| 2018 | Hotel Transylvania 3: Summer Vacation | Vlad (voice) | Film |
| 2016 | Ballerina | Luteau (US version) | Film |
| 2015 | Hotel Transylvania 2 | Vlad (voice) | Film |
| 2014 | Mr. Peabody & Sherman | Albert Einstein (voice) | Film |
| 2013 | Mel Brooks: Make a Noise | Self | Film |
| 2013 | Richard Pryor: Omit the Logic | Self | Film |
| 2012 | Mel Brooks Strikes Back! | Self | Film |
| 2011 | Mel Brooks and Dick Cavett Together Again | Self | Film |
| 2009 | Musical Mel: Inventing The Inquisition | Self | Film |
| 2008 | Spaceballs: The Totally Warped Animated Adventures | President Skroob/Yogurt | Film |
| 2008 | Spaceballs: The Animated Series | President Skroob / Yogurt (voice) | TV |
| 2008 | Spaceballs: The Animated Series | Executive Producer | TV |
| 2007 | Cutting Edge Comedians of the '60s & '70s | Self (archive footage) | Film |
| 2005 | Robots | Bigweld (voice) | Film |
| 2005 | The Producers | Producer | Film |
| 2004 | Broadway: The American Musical | Self | TV |
| 2003 | Jakers! The Adventures of Piggley Winks | Wiley (voice) | TV |
| 2002 | It's a Very Merry Muppet Christmas Movie | Joe Snow (voice) | Film |
| 2001 | Recording the Producers: A Musical Romp with Mel Brooks | Self / Host | Film |
| 2000 | Sex, Lies and Video Violence | Stressed old man | Film |
| 1999 | Screw Loose | Jake Gordon | Film |
| 1997 | Pretty as a Picture: The Art of David Lynch | Self | Film |
| 1995 | Dracula: Dead and Loving It | Prof. Abraham Van Helsing | Film |
| 1995 | Dracula: Dead and Loving It | Director | Film |
| 1995 | Dracula: Dead and Loving It | Producer | Film |
| 1994 | It's Alive: The True Story of Frankenstein | Self | Film |
| 1994 | The Little Rascals | Mr. Welling | Film |
| 1993 | Robin Hood: Men in Tights | Rabbi Tuckman | Film |
| 1993 | Robin Hood: Men in Tights | Director | Film |
| 1993 | Robin Hood: Men in Tights | Producer | Film |
| 1992 | The Vagrant | Executive Producer | Film |
| 1991 | Life Stinks | Goddard Bolt | Film |
| 1991 | Life Stinks | Director | Film |
| 1991 | Life Stinks | Producer | Film |
| 1990 | Look Who's Talking Too | Mr. Toilet Man (voice) | Film |
| 1989 | The Fly II | Producer | Film |
| 1987 | Spaceballs | President Skroob / Yogurt | Film |
| 1987 | Spaceballs | Director | Film |
| 1987 | Spaceballs | Producer | Film |
| 1983 | To Be or Not to Be | Dr. Frederick Bronski | Film |
| 1981 | History of the World: Part I | Moses / Comicus / Torquemada / Jacques / King Louis XVI | Film |
| 1981 | History of the World: Part I | Director | Film |
| 1979 | The Muppet Movie | Professor Max Krassman | Film |
| 1979 | The Muppets Go Hollywood | Self | Film |
| 1977 | High Anxiety | Dr. Richard H. Thorndyke | Film |
| 1977 | High Anxiety | Director | Film |
| 1977 | High Anxiety | Writer | Film |
| 1976 | Silent Movie | Mel Funn | Film |
| 1976 | Silent Movie | Director | Film |
| 1975 | The Adventure of Sherlock Holmes' Smarter Brother | Lion victim (voice) | Film |
| 1975 | The 2000 Year Old Man | 2000 Year Old Man (voice) | Film |
| 1975 | The 2000 Year Old Man | Writer | Film |
| 1974 | Free to Be… You and Me | Baby Boy (voice) | Film |
| 1974 | Young Frankenstein | Werewolf / Cat / Victor Frankenstein (voice) (uncredited) | Film |
| 1974 | Blazing Saddles | Governor William J. Le Petomane / Indian Chief | Film |
| 1974 | Young Frankenstein | Director | Film |
| 1974 | Blazing Saddles | Director | Film |
| 1971 | The Electric Company | Blond-Haired Cartoon Man (voice) | TV |
| 1970 | The Twelve Chairs | Tikon | Film |
| 1970 | The Twelve Chairs | Director | Film |
| 1970 | Shinbone Alley | Writer | Film |
| 1968 | The Producers | Director | Film |
| 1968 | The Producers | Writer | Film |
| 1963 | The Critic | Narrator (voice) | Film |
| 1963 | The Critic | Writer | Film |
| 1961 | The Ladies Man | Writer | Film |
| 1954 | New Faces | Writer | Film |
| CRASH BANDICOOT MOVIE | Doctor Nitrus Brio | Film |
| Untitled Nathan Lane Documentary | Self | Film |
| Funny Men in Tights: Three Generations of Comedy | Self | Film |